Fibroblast
Connective-tissue cell that synthesises collagen and the extracellular matrix.
For laboratory and research use only — not for human consumption.
Fibroblasts are the principal cellular component of connective tissue. They synthesise collagen (types I and III dominate in healing wounds), elastin, glycosaminoglycans, and matrix metalloproteinases, and they orchestrate the remodelling phase of wound healing. Specialised fibroblast subtypes include tenocytes (tendon), chondrocytes (cartilage), and myofibroblasts (the contractile, scar-forming phenotype induced by TGF-β). GHK-Cu is one of the most-studied research peptides for direct fibroblast transcriptional modulation; BPC-157 upregulates growth-hormone-receptor expression in tenocytes; AC-SDKP suppresses fibroblast-to-myofibroblast transition in anti-fibrotic models.