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Healing peptide library

Independent UK-focused profiles of the most-studied research peptides for tissue repair, wound healing, tendon and ligament recovery, gut integrity, and regeneration.

BPC-157

Body Protection Compound 157 · PL 14736 · Pentadecapeptide BPC 157

A 15-amino-acid pentadecapeptide derived from a protective protein found in human gastric juice. The most-studied healing research peptide, with extensive pre-clinical work on tendon, ligament, gut, and vascular repair.

tendon ligamentgut healinganti inflammatoryregeneration

TB-500

Thymosin Beta-4 fragment · Tβ4 17-23 · TB500

A synthetic peptide commonly described as a fragment of thymosin beta-4 incorporating the actin-binding 'LKKTETQ' motif. Studied for soft-tissue repair, wound healing, and cardiac tissue regeneration in animal models.

tendon ligamentskin woundregenerationanti inflammatory

GHK-Cu

Copper tripeptide-1 · Glycyl-L-histidyl-L-lysine:copper(II)

A naturally occurring copper-binding tripeptide (Gly-His-Lys) complexed with Cu(II). Extensively studied in dermatology for wound healing, collagen synthesis, antioxidant defence, and hair-follicle stimulation.

skin woundregenerationanti inflammatory

Thymosin Beta-4

Tβ4 · TMSB4X · Full-length thymosin beta-4 · RGN-352

A 43-amino-acid actin-sequestering peptide expressed in nearly all human cells. Distinct from the shorter TB-500 fragment; investigated in cardiac repair, corneal healing, neural regeneration, and dermal regeneration.

regenerationskin woundtendon ligamentanti inflammatory

Pentosan Polysulfate

PPS · PPS sodium · Elmiron · Cartrophen · SP54

A semi-synthetic sulfated polysaccharide investigated in osteoarthritis, interstitial cystitis, and connective-tissue research for its chondroprotective, anti-inflammatory, and anticoagulant effects — with a critical long-term safety signal regarding pigmentary maculopathy.

jointanti inflammatory

KPV

α-MSH 11-13 · Lysine-Proline-Valine tripeptide · alpha-MSH C-terminal fragment

A three-amino-acid C-terminal fragment of α-MSH studied for its anti-inflammatory effects in colitis, atopic skin conditions, and mucosal healing models — without the pigmentary effects of full-length MSH.

gut healinganti inflammatory

LL-37

Cathelicidin LL-37 · hCAP-18 fragment · Human cathelicidin antimicrobial peptide

The only human cathelicidin antimicrobial peptide — a 37-residue cationic amphipathic helix studied for direct antimicrobial action, wound healing, angiogenesis, and dual-edged modulation of host innate immune responses.

antimicrobialskin wound

AOD-9604

hGH 177-191 analogue · Tyr-hGH(177-191) · Anti-Obesity Drug 9604

A 16-amino-acid C-terminal analogue of human growth hormone, originally investigated for lipolytic activity without IGF-1 effects, and subsequently studied for cartilage repair and post-injury recovery.

regenerationjoint

AC-SDKP (TB-500 Fragment)

AcSDKP · N-acetyl-Ser-Asp-Lys-Pro · Goralatide · Acetyl-Ser-Asp-Lys-Pro · N-Acetyl-SDKP

A naturally occurring N-terminal tetrapeptide released from thymosin beta-4 by prolyl oligopeptidase. AC-SDKP circulates endogenously, is rapidly degraded by angiotensin-converting enzyme (ACE), and is studied primarily for anti-fibrotic, pro-angiogenic, and haematopoietic regulatory effects across cardiac, renal, and pulmonary tissue.

regenerationanti inflammatory

Epitalon

Epithalon · Epithalone · Tetrapeptide AEDG · Epithalamin tetrapeptide

A synthetic tetrapeptide (Ala-Glu-Asp-Gly) modelled on the bovine pineal extract epithalamin. Investigated primarily in Russian gerontology research for effects on telomerase activity in cultured somatic cells, circadian rhythm normalisation in aged animals, and antioxidant defence. Evidence is largely confined to one research network and independent replication is limited.

regeneration

Larazotide

Larazotide acetate · AT-1001 · INN-202 · Larazotide acetate (INEFC-002)

An eight-amino-acid synthetic peptide functioning as a tight-junction regulator and zonulin antagonist. Designed for luminal delivery with minimal systemic absorption, larazotide has been investigated in multiple Phase II trials for coeliac disease with persistent symptoms, and represents the furthest-advanced clinical programme for a peptide targeting intestinal barrier function.

gut healing