Tissue regeneration research peptides
Regeneration research peptides operate at the intersection of progenitor-cell biology, cellular senescence, and extracellular-matrix remodelling. Thymosin beta-4 and AC-SDKP are the most-cited examples; epitalon represents the cellular-ageing angle.
Peptides in this category
BPC-157
Body Protection Compound 157 · PL 14736 · Pentadecapeptide BPC 157
A 15-amino-acid pentadecapeptide derived from a protective protein found in human gastric juice. The most-studied healing research peptide, with extensive pre-clinical work on tendon, ligament, gut, and vascular repair.
TB-500
Thymosin Beta-4 fragment · Tβ4 17-23 · TB500
A synthetic peptide commonly described as a fragment of thymosin beta-4 incorporating the actin-binding 'LKKTETQ' motif. Studied for soft-tissue repair, wound healing, and cardiac tissue regeneration in animal models.
GHK-Cu
Copper tripeptide-1 · Glycyl-L-histidyl-L-lysine:copper(II)
A naturally occurring copper-binding tripeptide (Gly-His-Lys) complexed with Cu(II). Extensively studied in dermatology for wound healing, collagen synthesis, antioxidant defence, and hair-follicle stimulation.
Thymosin Beta-4
Tβ4 · TMSB4X · Full-length thymosin beta-4 · RGN-352
A 43-amino-acid actin-sequestering peptide expressed in nearly all human cells. Distinct from the shorter TB-500 fragment; investigated in cardiac repair, corneal healing, neural regeneration, and dermal regeneration.
AOD-9604
hGH 177-191 analogue · Tyr-hGH(177-191) · Anti-Obesity Drug 9604
A 16-amino-acid C-terminal analogue of human growth hormone, originally investigated for lipolytic activity without IGF-1 effects, and subsequently studied for cartilage repair and post-injury recovery.
AC-SDKP (TB-500 Fragment)
AcSDKP · N-acetyl-Ser-Asp-Lys-Pro · Goralatide · Acetyl-Ser-Asp-Lys-Pro · N-Acetyl-SDKP
A naturally occurring N-terminal tetrapeptide released from thymosin beta-4 by prolyl oligopeptidase. AC-SDKP circulates endogenously, is rapidly degraded by angiotensin-converting enzyme (ACE), and is studied primarily for anti-fibrotic, pro-angiogenic, and haematopoietic regulatory effects across cardiac, renal, and pulmonary tissue.
Epitalon
Epithalon · Epithalone · Tetrapeptide AEDG · Epithalamin tetrapeptide
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) modelled on the bovine pineal extract epithalamin. Investigated primarily in Russian gerontology research for effects on telomerase activity in cultured somatic cells, circadian rhythm normalisation in aged animals, and antioxidant defence. Evidence is largely confined to one research network and independent replication is limited.
Relevant research stacks
Tendon & Ligament Research Stack
Combine peptides studied for soft-tissue, vascular, and cellular-migration effects in tendon and ligament repair research.
Gut Healing Research Stack
Examine complementary effects on mucosal repair, inflammatory cytokine release, and tight-junction integrity in pre-clinical gut models.
Skin & Wound Healing Research Stack
Address dermal collagen synthesis, angiogenesis, and antimicrobial defence in pre-clinical wound-healing models.
Relevant comparisons
BPC-157 vs TB-500
BPC-157 and TB-500 are the two most-discussed research peptides in soft-tissue repair. They have overlapping interest areas — tendon, ligament, and vascular healing — but operate by different mechanisms and rest on quite different bodies of evidence.
GHK-Cu vs TB-500
GHK-Cu and TB-500 are sometimes grouped together as 'tissue-repair peptides', but the two operate at very different scales — GHK-Cu primarily as a transcriptional modulator of dermal fibroblasts, TB-500 primarily as a cell-migration peptide.
BPC-157 vs AOD-9604
Both BPC-157 and AOD-9604 are discussed in the context of post-injury recovery, but they originate from very different research programmes and target different tissues.
Where to source research peptides for laboratory research
The following UK-based suppliers stock research-grade, lyophilised peptides for in-vitro and pre-clinical work. Purity and provenance vary; always request a Certificate of Analysis (CoA) and confirm cold-chain storage on arrival. None of the products linked below are approved for human use.
- PeptideAuthority.co.uk
UK-based research peptide supplier with batch certificates of analysis and >99% purity testing.
- PeptideBarn.co.uk
Wide catalogue of research-grade lyophilised peptides shipped from the UK, including bulk vials.