Half-life
Time for the plasma concentration of a substance to fall to half its initial value.
For laboratory and research use only — not for human consumption.
Half-life is a derived pharmacokinetic parameter from the elimination phase of a concentration-time curve. Most research peptides have short plasma half-lives (minutes to hours) because they are rapidly cleaved by circulating peptidases or cleared by the kidneys. BPC-157 is reported to have a sub-hour plasma half-life in rodents; AC-SDKP is degraded primarily by ACE; AOD-9604 has roughly a 30-minute clinical half-life. Short plasma half-life does not preclude longer-lived tissue effects, particularly for peptides that bind to local receptors or accumulate in target tissue.