Angiogenesis
The formation of new blood vessels from pre-existing vasculature.
For laboratory and research use only — not for human consumption.
Angiogenesis is the process by which new capillaries sprout from existing vessels, distinct from vasculogenesis (de-novo vessel formation from progenitor cells). It is a central mechanism in tissue repair, granulation tissue formation, and chronic disease (tumour growth, diabetic retinopathy). In peptide research, angiogenic effects are most strongly associated with BPC-157 (VEGFR2-Akt-eNOS signalling), thymosin beta-4 (laminin-5 and angiopoietin-2 upregulation), and LL-37 (FPR2-mediated endothelial proliferation). Standard pre-clinical assays include tube formation in cultured endothelial cells (HUVEC), the chick chorioallantoic membrane (CAM) assay, and quantification of microvessel density in healing tissue sections.